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TDI-012804

CAT: 0013-GTR19258367-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19258367-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TDI-012804 is a TNKS2 inhibitor that selectively inhibits endogenous TNKS2 protein within cells. It enhances the expression of AXIN1 protein in Tnks1 heterozygous (Tnks1HET) and knockout (Tnks1KO) cells. TDI-012804 suppresses the proliferation of ApcQ1405X/Tnks1KO organoids with an EC50 of 59.1 nM and exhibits selective toxicity towards Tnks1KO AKP-G12D and AKP-G13D organoids.
Field of Research
Epigenetics & Chromatin, Molecular Biology
Storage Conditions
-20°C
Notes
For research use only.

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