EGFR-IN-62

CAT: 0931-T63895-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T63895-01Size:25 mg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Apoptosis, EGFR, Others

Related Pathways

Apoptosis, Others, JAK/STAT signaling, Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

EGFR-IN-62 is a potent inhibitor of EGFR kinase with IC50 values of 10 nM for L858R/T790 M, 29 nM for WT and 2 42 nM for L858R/T790 M/C797S. EGFR-IN-62 blocks the cell cycle of A549 and/or H1975 cells in G1/G0 phase and induces apoptosis and motility inhibition. EGFR-IN-62 effectively inhibited the proliferation of A549 (IC50: 2.53 μM) and H1975 cells (IC50: 1.56 μM) .

Molecular Formula

C30H33N9O2

Molecular Weight

551.64

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-147862	EGFR-IN-62
CKM-0020-01	KBA.62 (KBA.62), MMab
MBS395678-01	KSHV/HHV8 (mal 62/ORF 62)
A8180-5	KN-62
FB24811-01	KN 62
HY-174449	HDAC6-IN-62
MBS7166688	62 Antibody
GTR19273115-01	HPK1-IN-62
HY-107084	TT-62
ARC0110	CAL-62

EGFR-IN-62

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