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HPK1-IN-62

CAT: 0013-GTR19273115-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19273115-01Size:10 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HPK1-IN-62 is a selective, orally active inhibitor of HPK-1 with an IC50 of 1.22 nM. It significantly enhances selectivity for GLK (> 665-fold) and LCK (> 1095-fold) . HPK1-IN-62 boosts T cell activation and shows synergy with anti-mPD-1 therapy in inhibiting tumor growth in the MC38 tumor model. It is applicable for research in colon cancer and cancer immunotherapy.
Storage Conditions
-20°C
Notes
For research use only.

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