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PLK1-IN-4

CAT: 0931-T63886-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T63886-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2622273-55-4
Target
Apoptosis, Cell Cycle Arrest, PLK
Related Pathways
Apoptosis, Cell Cycle/Checkpoint
Purity
0.9994
Bioactivity
PLK1-IN-4 (compound 31) is a selective PLK1 inhibitor (IC50 < 0.51 nM) exhibiting antiproliferative activity against multiple cancer cell lines including A549, HT-29, and HCT-116. It induces cell cycle arrest and apoptosis, making it suitable for hepatocellular carcinoma research.
Smiles
O=C(OC)C=1SC=CC1NC2=NC(=NC=C2C(F)(F)F)NC=3C=C4C(=CC3OC)CCN4C(=O)CN(C)C
Molecular Formula
C24H25F3N6O4S
Molecular Weight
550.55
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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