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Bcl-2-IN-6

CAT: 0931-T63676-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63676-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, Apoptosis, Bcl-2 Family, Caspase, MDM-2/p53
Related Pathways
Proteases/Proteasome, Apoptosis, Others
Bioactivity
Bcl-2-IN-6 is a potent inhibitor of Bcl-2 (b-cell lymphoma-2) that downregulates Bcl-2 expression and increases the expression of p53, Bax, and caspase-7 mRNA. bcl-2-IN-7 induces cell cycle arrest and apoptosis in breast cancer MCF-7 cells. bcl-2-IN-7 acts on MCF-7 cells (Bcl2-IN-7 showed good antitumor effects on MCF-7 cells (IC50: 20.91 μM), LoVo cells (IC50: 22.30 μM), HepG2 cells (IC50: 42.29 μM) and A549 cells (IC50: 48.00 μM) .
Molecular Formula
C25H24N4O5S2
Molecular Weight
524.61
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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