WF-47-JS03

• Target:

  Others|||c-RET

• Related Pathways:

  Tyrosine Kinase/Adaptors|||Apoptosis|||Others

• Bioactivity:

  WF-47-JS03 is a selective and potent inhibitor of RET kinase that crosses the blood-brain barrier and is more than 500-fold more selective for the kinase insertion domain receptor (KDR) .WF-47-JS03 acts on Ba/F3 cells transfected with KIF5B-RET (IC50: 1.7 nM) and LC-2/ad lung cancer cells transfected with CCDC6-RET (IC50: 5.3 nM) . cells (IC50: 5.3 nM) .

• Molecular Formula:

  C30H38N6O2

• Molecular Weight:

  514.66

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C