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WF-47-JS03

CAT: 0931-T63573-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63573-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Others, c-RET
Related Pathways
Tyrosine Kinase/Adaptors, Apoptosis, Others
Bioactivity
WF-47-JS03 is a selective and potent inhibitor of RET kinase that crosses the blood-brain barrier and is more than 500-fold more selective for the kinase insertion domain receptor (KDR) .WF-47-JS03 acts on Ba/F3 cells transfected with KIF5B-RET (IC50: 1.7 nM) and LC-2/ad lung cancer cells transfected with CCDC6-RET (IC50: 5.3 nM) . cells (IC50: 5.3 nM) .
Molecular Formula
C30H38N6O2
Molecular Weight
514.66
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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