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CHIR-124

CAT: 0931-T6350-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T6350-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
405168-58-3
Target
Src, Chk, FLT, Apoptosis, GSK-3, PDGFR
Related Pathways
Apoptosis, PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Angiogenesis, Tyrosine Kinase/Adaptors, Stem Cells
Purity
0.9835
Bioactivity
CHIR-124 is an effective Chk1 inhibitor (IC50: 0.3 nM) . It has 2, 000-fold selectivity against Chk2, 500- to 5, 000-fold less activity against Cdc2 and CDK2/4.
Smiles
Clc1ccc2[nH]c(=O)c(-c3nc4ccccc4[nH]3)c(N[C@@H]3CN4CCC3CC4)c2c1
Molecular Formula
C23H22ClN5O
Molecular Weight
419.91
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
A8394-50CHIR-124
444297-01CHIR 124

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