CHIR-99021

• Target :

  Wnt/beta-catenin|||Autophagy|||GSK-3

• Related Pathways :

  Cytoskeletal Signaling|||PI3K/Akt/mTOR signaling|||Stem Cells|||Autophagy

• Purity :

  0.9929

• Bioactivity :

  CHIR-99021 (CT99021) is an activator of the Wnt/?-catenin signaling pathway and a GSK-3?/? inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in mouse and human embryonic stem cells.

• Smiles :

  Cc1c[nH]c(n1)-c1cnc(NCCNc2ccc(cn2)C#N)nc1-c1ccc(Cl)cc1Cl

• Molecular Formula :

  C22H18Cl2N8

• Molecular Weight :

  465.34

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  252917-06-9