BCR-ABL-IN-6

CAT: 0931-MF-0045770-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0045770-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2499499-26-0
Target
Others|||Bcr-Abl
Related Pathways
Others|||Angiogenesis|||Tyrosine Kinase/Adaptors|||Cytoskeletal Signaling
Bioactivity
BCR-ABL-IN-6 (9h) is an imatinib derivative and a selective inhibitor of Bcr-Abl kinase, showing activity on Bcr-AblWT (IC50: 4.6 nM) and Bcr-AblT3151 (IC50: 277 nM) . BCR-ABL-IN-6 (9h) is utilized in studying chronic myeloid leukemia treatment.
Smiles
C(F)(F)(F)C1=C(C=CC(C(NC2=CC(C#CC3=C4C(NN=C4N)=CC=C3)=CC=C2)=O)=C1)N5CCOCC5
Molecular Formula
C27H22F3N5O2
Molecular Weight
505.49
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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