BCR-ABL-IN-6

CAT: 0931-T63450-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T63450-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

2499499-26-0

Target

Others, Bcr-Abl

Related Pathways

Others, Angiogenesis, Tyrosine Kinase/Adaptors, Cytoskeletal Signaling

Bioactivity

BCR-ABL-IN-6 (9h) is an imatinib derivative and a selective inhibitor of Bcr-Abl kinase, showing activity on Bcr-AblWT (IC50: 4.6 nM) and Bcr-AblT3151 (IC50: 277 nM) . BCR-ABL-IN-6 (9h) is utilized in studying chronic myeloid leukemia treatment.

Smiles

C(F)(F)(F)C1=C(C=CC(C(NC2=CC(C#CC3=C4C(NN=C4N)=CC=C3)=CC=C2)=O)=C1)N5CCOCC5

Molecular Formula

C27H22F3N5O2

Molecular Weight

505.49

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BCR-ABL-IN-6

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