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ZLMT-12

CAT: 0931-T63144-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63144-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
Cholinesterase (ChE), Apoptosis, Others, CDK
Related Pathways
Apoptosis, Others, Neuroscience, Cell Cycle/Checkpoint
Bioactivity
ZLMT-12 (compound 35) is a tacrine derivative and a potent inhibitor of CDK2 (IC50: 0.011 μM) and CDK9 (IC50: 0.002 μM) . ZLMT-12 weakly inhibits AChE (IC50: 19.023 μM) and BuChE (IC50: 2.768 μM) . ZLMT-12 has anti-proliferative activity and low cytotoxicity. ZLMT-12 blocks the cell cycle in S-phase and G2/M-phase and induces apoptosis.
Molecular Formula
C26H31ClN6O
Molecular Weight
479.02
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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