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EGFR-IN-45

CAT: 0931-T63070-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T63070-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
EGFR, Apoptosis, Others, Topoisomerase, CDK
Related Pathways
Cell Cycle/Checkpoint, Others, Tyrosine Kinase/Adaptors, Angiogenesis, DNA Damage/DNA Repair, JAK/STAT signaling, Apoptosis
Bioactivity
EGFR-IN-45 is a potent pan-inhibitor of the epidermal growth factor receptor (EGFR) with an IC50 of 0.4 μM and also targets CDK2 with an IC50 of 1.6 μM. It inhibits topoisomerases Topo I and Topo II, blocks the cancer cell cycle in the pre-G1 phase, and induces apoptosis.
Molecular Formula
C28H23N7O
Molecular Weight
473.53
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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Alternative Products

CatalogName
GTR19185968-01EGFR-IN-45
sc-80543EGFR (EGFR.1)
ant-042EGFR

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