MK-8153

• Target:

  Others|||Potassium Channel

• Related Pathways:

  Membrane transporter/Ion channel|||Others

• Bioactivity:

  MK-8153 is a selective, potent, orally active inhibitor of extrarenal medullary potassium channels (ROMK), acting on ROMK EP (IC50: 5 ?M) and hERG EP (IC50: 34 ?M) .MK-8153 can be used as a diuretic.

• Smiles:

  O=C1C2(CCN1C3=C(C)C(=O)OC3)CCN(C[C@H](O)C=4C(C)=C5C(=CC4)C(=O)OC5)CC2

• Molecular Formula:

  C24H28N2O6

• Molecular Weight:

  440.49

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1548286-45-8