J-1063

• CAS Number :

  2374772-46-8

• Target :

  Others|||TGF-beta/Smad

• Related Pathways :

  Others|||Stem Cells

• Bioactivity :

  J-1063 is a selective, orally active and potent inhibitor of ALK5 (IC50: 0.039 ?M) . J-1063 inhibits inflammatory infiltration, collagen deposition, hepatocyte necrosis and exhibits anti-fibrotic effects. j-1063 has potential for liver fibrosis studies.

• Smiles :

  C(C(NC1=CC=CC=C1)=O)N2C=C(C(=N2)C=3N=C(C)C=CC3)C4=CC=5C(S4)=CC=NC5

• Molecular Formula :

  C24H19N5OS

• Molecular Weight :

  425.51

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C