(±) -J 113397

• Target :

  Others|||Opioid Receptor

• Related Pathways :

  GPCR/G Protein|||Endocrinology/Hormones|||Neuroscience|||Others

• Bioactivity :

  (±) -J-113397 is a potent and selective non-peptidyl ORL1 receptor antagonist (K (i) : cloned human ORL1=1.8 nM) . J-113397 inhibited nociceptin/orphanin FQ-stimulated GTP?S binding to CHO cells expressing ORL1 with an IC50 value of 5.3 nM. J-113397 can be used for researching the physiological roles of nociceptin/orphanin FQ [1].

• Smiles :

  O=C1N(C=2C(N1CC)=CC=CC2)[C@@H]3[C@@H](CO)CN(CC4CCCCCCC4)CC3

• Molecular Formula :

  C24H37N3O2

• Molecular Weight :

  399.57

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  217461-40-0