EGFR-IN-49

• Target :

  Others|||EGFR

• Related Pathways :

  Tyrosine Kinase/Adaptors|||JAK/STAT signaling|||Angiogenesis|||Others

• Bioactivity :

  EGFR-IN-49 is a potent and selective EGFR inhibitor that targets EGFRT790M (IC50: 65.0 nM) and EGFRT790M/L858R (IC50: 13.6 nM), inducing apoptosis in a dose-dependent manner.

• Smiles :

  O(C1=C2C(=NC(NC3=CC(C#N)=CC=C3)=N1)C=CS2)C4=CC(NC(C=C)=O)=CC=C4

• Molecular Formula :

  C22H15N5O2S

• Molecular Weight :

  413.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2459932-81-9