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EGFR-IN-49

CAT: 0931-T62113-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62113-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2459932-81-9
Target
Others, EGFR
Related Pathways
Tyrosine Kinase/Adaptors, JAK/STAT signaling, Angiogenesis, Others
Bioactivity
EGFR-IN-49 is a potent and selective EGFR inhibitor that targets EGFRT790M (IC50: 65.0 nM) and EGFRT790M/L858R (IC50: 13.6 nM), inducing apoptosis in a dose-dependent manner.
Smiles
O(C1=C2C(=NC(NC3=CC(C#N)=CC=C3)=N1)C=CS2)C4=CC(NC(C=C)=O)=CC=C4
Molecular Formula
C22H15N5O2S
Molecular Weight
413.45
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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