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PI3Kδ-IN-10

CAT: 0931-T62013-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T62013-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2409725-49-9
Target
Others, PI3K, Apoptosis, Akt
Related Pathways
PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling, Apoptosis
Bioactivity
PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50 = 2 nM) that robustly suppresses the downstream AKT pathway to induce subsequent apoptosis in hepatocellular carcinoma models.
Smiles
[C@H](NC=1C(C#N)=C(N)N=C(N)N1)(C)C=2C=3C(N(N2)C=4C=CC=NC4)=CC(Cl)=CC3
Molecular Formula
C19H16ClN9
Molecular Weight
405.84
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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