CHMFL-PI4K-127

• Target:

  Others|||PI3K|||PI4K

• Related Pathways:

  Others|||PI3K/Akt/mTOR signaling

• Bioactivity:

  CHMFL-PI4K-127 (compound 15g) is a highly selective inhibitor of PfPI4K (Plasmodium falciparum PI4K kinase) with oral activity (IC50=0.9 nM) and exhibits strong inhibitory activity against Plasmodium falciparum 3D7 (EC50=25.1 nM), demonstrating significant anti-malaria effects.

• Smiles:

  N(S(=O)(=O)C1=CC=CC=C1)C2=CC(=CN=C2Cl)C=3C=C(C(NC)=O)C=NC3

• Molecular Formula:

  C18H15ClN4O3S

• Molecular Weight:

  402.85

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2377604-81-2