BACE1-IN-12

• Target:

  Others|||Beta-Secretase

• Related Pathways:

  Neuroscience|||Others

• Bioactivity:

  BACE1-IN-12 is a potent BACE1 inhibitor (IC50: 8.9 ?M) that can cross the blood-brain barrier. BACE1-IN-12 selectively inhibits BuChE (butylcholinesterase) activity (IC50: 3.2 ?M) . BACE1-IN-12 has potential for anti-Alzheimer's disease studies.

• Smiles:

  N(C1=C(N=C2N1C=CC=C2)C3=CC=C(OCC4=CN(CC5=CC(Cl)=C(Cl)C=C5)N=N4)C=C3)C6CCCCC6

• Molecular Formula:

  C29H28Cl2N6O

• Molecular Weight:

  547.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2479315-19-8