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Anticancer agent 42

CAT: 0931-T61777-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61777-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2687265-18-3
Target
Others, Apoptosis, Reactive Oxygen Species, MDM-2/p53
Related Pathways
Others, NF-κB, Immunology/Inflammation, Apoptosis, Metabolism
Bioactivity
Anticancer agent 42 (compound 10d) is an orally active, potent anticancer agent with an IC50 of 0.07 μM against MDA-MB-231 cells. It exerts anticancer activity by activating apoptotic pathways and p53 expression. Anticancer agent 42 is a valuable tool for investigating metastatic breast cancer [1].
Smiles
CC1=C(C=2C(N1)=CC=CC2)C=3C(=O)C(=C(Cl)C(=O)C3Cl)N4CCOCC4
Molecular Formula
C19H16Cl2N2O3
Molecular Weight
391.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C