SHP2-IN-9

CAT: 0931-T61701Size: 2 mgDry Ice: NoHazardous: No

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CAT#:0931-T61701Size:2 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

Others, Phosphatase

Related Pathways

Others, Metabolism

Bioactivity

SHP2-IN-9 is a potent inhibitor (IC50 = 1.174 μM) specifically targeting the SHP2 protein, displaying improved penetration across the blood-brain barrier. It exhibits a remarkable 85-fold selectivity for SHP2 over SHP1. By inhibiting SHP2-mediated cell signal transduction and impairing cancer cell proliferation, SHP2-IN-9 effectively suppresses the growth of both cervix cancer tumors and glioblastoma in vivo [1].

Molecular Formula

C20H20FN3O2S

Molecular Weight

385.46

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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BA8113-5	SHP2-IN-9
E8ET1611-80	SHP2
GTR18155704	SHP2 Antibody
HY-172911-01	SHP2-IN-37
HY-172454	SHP2-IN-36
HY-171959	SHP2-IN-39
HY-176796	SHP2-IN-43
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HY-155276	SHP2-IN-20
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SHP2-IN-9

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