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Anticancer agent 56

CAT: 0931-T61673-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61673-01Size:25 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2241915-59-1
Target
Reactive Oxygen Species, Caspase, Apoptosis, Bcl-2 Family, Others
Related Pathways
Proteases/Proteasome, Immunology/Inflammation, NF-κB, Others, Apoptosis, Metabolism
Bioactivity
Anticancer agent 56 (compound 4d) is a powerful anti-cancer compound with favorable drug-like properties, showing significant anticancer activity against multiple cancer cell lines with an IC50 value of less than 3 μM. It exerts its effects by causing cell cycle arrest at the G2/M phase and activating the mitochondrial apoptosis pathway, inducing the accumulation of reactive oxygen species (ROS), upregulating BAX, downregulating Bcl-2, and triggering the activation of caspases 3, 7, and 9 [1].
Smiles
CC=1N(N=NC1C(/C=C/C2=CC(OC)=C(OC)C=C2)=O)C3=CC=C(Cl)C=C3
Molecular Formula
C20H18ClN3O3
Molecular Weight
383.83
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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