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Anticancer agent 57

CAT: 0931-T61582-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61582-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2408017-71-8
Target
Others, Apoptosis
Related Pathways
Others, Apoptosis
Bioactivity
Anticancer agent 57 (compound 14) demonstrates potent inhibition of MDA-MB-231, MDA-MB-468, and MCF-7 cell lines, with IC50 values ranging from 6.43 to 8.00 μM. Additionally, this agent induces cell cycle arrest and promotes apoptosis. In vivo studies using nude mice xenografted with MADMB-231 cells have shown that Anticancer agent 57 effectively inhibits tumor growth. Consequently, Anticancer agent 57 can serve as a valuable tool for researching triple negative breast cancer (TNBC) [1].
Smiles
N(CCCl)(CCCl)C1=CC=C(/C=C/C(=O)C2=CC(OC)=CC=C2)C=C1
Molecular Formula
C20H21Cl2NO2
Molecular Weight
378.29
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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