USP15-IN-1

• Target:

  DUB

• Related Pathways:

  DNA Damage/DNA Repair|||Ubiquitination|||Cell Cycle/Checkpoint

• Purity:

  0.9981

• Bioactivity:

  USP15-IN-1 is a potent USP15 inhibitor (IC50 is 3.76 ?M) with high antiproliferative activity against non-small cell lung cancer and leukemia cells. As an interacting protein of cGAS, USP15 promotes cGAS to recognize DNA and activate downstream signaling pathways.

• Smiles:

  OCCNC(=O)c1ccc2[nH]c3CN(CCc3c2c1)C(=O)Cc1ccccc1

• Molecular Formula:

  C22H23N3O3

• Molecular Weight:

  377.44

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2260826-16-0