USP5-IN-1

• Target :

  DUB

• Related Pathways :

  Ubiquitination|||Cell Cycle/Checkpoint|||DNA Damage/DNA Repair

• Purity :

  0.9976

• Bioactivity :

  USP5-IN-1 (compound 64) is a potent deubiquitinase USP5 inhibitor that binds to the USP5 ZnF-UBD with a KD of 2.8 ?M and is selective over nine proteins containing structurally similar ZnF-UBD domains. Additionally, USP5-IN-1 inhibits the USP5 catalytic cleavage of a di-ubiquitin substrate [1].

• Smiles :

  O=C(O)CNC(=O)C1=CC=C(S(=O)(=O)N2CCC(C3=CC=C(Cl)C=C3)CC2)C=N1

• Molecular Formula :

  C19H20ClN3O5S

• Molecular Weight :

  437.9

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C