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NLRP3-IN-10

CAT: 0931-T61392-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T61392-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2641826-39-1
Target
NOD-like Receptor (NLR), NOD
Related Pathways
NF-κB, Immunology/Inflammation
Purity
0.9963
Bioactivity
NLRP3-IN-10 (ZVN26391) is a potent NLRP3 inhibitor. NLRP3-IN-10 inhibits IL-1β release with an IC50 value of 251.1 nM. NLRP3-IN-10 attenuates ASC speck formation, leading to suppress activation of NLRP3 inflammasome.
Smiles
COc1cc(\C=C\C(=O)c2ccc(F)cc2)c(OC)cc1Br
Molecular Formula
C17H14BrFO3
Molecular Weight
365.19
Shipping Conditions
Ice Packs
Storage Temperature
-20°C