Products for Research Use Only

BRD4 Inhibitor-15

CAT: 0931-T61327-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T61327-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2761366-60-1
Target
Bcl-2 Family, Epigenetic Reader Domain, c-Myc, Caspase, Apoptosis, Others
Related Pathways
Others, Proteases/Proteasome, Chromatin/Epigenetic, Apoptosis, Cell Cycle/Checkpoint
Bioactivity
BRD4 Inhibitor-15 (compound 13) is a highly potent and specific BRD4 inhibitor with an IC50 of 18 nM, inducing apoptosis in 22RV1 cells by regulating Bcl-2/Bax proteins and activating caspase-3 signaling, and down-regulating c-Myc levels, making it valuable for prostate cancer research [1].
Smiles
C(N1C=2C(=CC=C(C2)C=3C(OCC)=CC(=O)N(C)C3)C=N1)C4=CC=CC=C4
Molecular Formula
C22H21N3O2
Molecular Weight
359.42
Shipping Conditions
Ice Packs
Storage Temperature
-20°C