NAB-14

• Target:

  IGluR|||Others

• Related Pathways:

  Membrane transporter/Ion channel|||Others|||Neuroscience

• Bioactivity:

  NAB-14 is a powerful and selective chemical compound that acts as a non-competitive antagonist for GluN2C and GluN2D receptors. With an IC50 value of 580 nM for GluN1/GluN2D, NAB-14 demonstrates high potency. This compound exhibits a remarkable selectivity of more than 800-fold towards recombinant GluN2C and GluN2D when compared to GluN2A and GluN2B. Furthermore, NAB-14 possesses the ability to penetrate the blood-brain-barrier effectively [1].

• Smiles:

  N(C(=O)C1=CC=C(OC(N(CC)CC)=O)C=C1)C2=C3C(C=CN3)=CC=C2

• Molecular Formula:

  C20H21N3O3

• Molecular Weight:

  351.4

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1237541-73-9