NAB-14

CAT: 0931-T61227-01Size: 25 mgDry Ice: NoHazardous: No

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CAT#:0931-T61227-01Size:25 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1237541-73-9

Target

IGluR, Others

Related Pathways

Membrane transporter/Ion channel, Others, Neuroscience

Bioactivity

NAB-14 is a powerful and selective chemical compound that acts as a non-competitive antagonist for GluN2C and GluN2D receptors. With an IC50 value of 580 nM for GluN1/GluN2D, NAB-14 demonstrates high potency. This compound exhibits a remarkable selectivity of more than 800-fold towards recombinant GluN2C and GluN2D when compared to GluN2A and GluN2B. Furthermore, NAB-14 possesses the ability to penetrate the blood-brain-barrier effectively [1].

Smiles

N(C(=O)C1=CC=C(OC(N(CC)CC)=O)C=C1)C2=C3C(C=CN3)=CC=C2

Molecular Formula

C20H21N3O3

Molecular Weight

351.4

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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