Nab-Paclitaxel

• UNSPSC Description:

  Nab-Paclitaxel is an albumin-bound nanoparticle formulation of Paclitaxel (HY-B0015). Nab-Paclitaxel is composed of albumin and the active pharmaceutical ingredient Paclitaxel (Paclitaxel: human albumin=1:9), in which human albumin is used as an excipient to disperse and stabilize particles and carry the main drug. Nab-Paclitaxel was associated with higher response rates and better tolerability, with favorable pharmacokinetic properties[1][2]. (The product size below only indicate the effective content of Paclitaxel. The actual albumin quality depends on the batch. The ratio of each component in this product is Paclitaxel: albumin = 1:7-1:11.)

• Target Antigen:

  Apoptosis; Autophagy; Microtubule/Tubulin

• Type:

  Inhibitory Antibodies

• Related Pathways:

  Apoptosis;Autophagy;Cell Cycle/DNA Damage;Cytoskeleton

• Applications:

  Cancer-programmed cell death

• Field of Research:

  Cancer

• Assay Protocol:

  https://www.medchemexpress.com/nab-paclitaxel.html

• Purity:

  99.70

• Solubility:

  H2O : < 0.1 mg/mL (ultrasonic)

• Smiles:

  [Nab-Paclitaxel]

• References & Citations:

  [1]Yardley DA. nab-Paclitaxel mechanisms of action and delivery. J Control Release. 2013 Sep 28;170(3):365-72.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4°C for 2 years, do not freeze

• Clinical Information:

  Phase 4