FGFR-IN-14

CAT: 0931-T210281-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T210281-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Target

FGFR

Related Pathways

Tyrosine Kinase/Adaptors, Angiogenesis

Bioactivity

FGFR-IN-14 (compound 10h) is a pan-FGFR inhibitor. It effectively inhibits FGFR1, FGFR2, FGFR3, and the FGFR2V564F gatekeeper mutant, with IC50 values of 46, 41, 99, and 62 nM, respectively. Additionally, FGFR-IN-14 demonstrates strong antiproliferative effects on NCI-H520 lung cancer cells and SNU-16 and KATO III gastric cancer cells, with IC50 values of 19, 59, and 73 nM, respectively.

Molecular Formula

C24H19F2N7O2

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Catalog	Name
HY-162577	FGFR-IN-14
378470	FGFR
BA8935-100	FGFR-IN-1
HY-147621	FGFR-IN-6
HY-168653	FGFR-IN-15
HY-142921	FGFR-IN-2
HY-163527	FGFR-IN-13
HY-147620	FGFR-IN-5
HY-174268	FGFR-IN-21
HY-172923	FGFR-IN-20

FGFR-IN-14

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