Products for Research Use Only

TGFβRI-IN-4

CAT: 0013-GTR19186040-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19186040-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TGFβRI-IN-4 is a potent, orally bioavailable inhibitor of TGFβ receptor I (ALK5) kinase, demonstrating activity in cellular assays (e.g., NIH3T3 cells) and in vivo xenograft models where it reduces tumor growth. This compound is a valuable research tool for studying TGF-β signaling in oncology, fibrosis, and immunology research.
CAS Number
2421135-03-5
Field of Research
Stem Cell & Developmental Biology
Smiles
O (C=1C (=NN (C1) C2CC2) C3CC (F) (F) C3) C=4C=C (NC=5C=C (C (C) (C) O) N=CC5) N=CC4
Molecular Formula
C23H25F2N5O2
Molecular Weight
441.47
Storage Conditions
-20°C
Notes
For research use only.