(Rac) -Indoximod

• Target:

  Others|||Apoptosis|||Indoleamine 2,3-Dioxygenase (IDO) |||IDO

• Related Pathways:

  Apoptosis|||Others|||Metabolism

• Bioactivity:

  (Rac) -Indoximod (1-Methyl-DL-tryptophan) is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO) . Combined treatment with IFN-? and (Rac) -Indoximod significantly suppresses the activity of ?-SMA-expressing human cardiac myofibroblasts (hCMs) and promotes apoptosis by up-regulating the genes IRF-1, Fas, and FasL, effectively improving cardiac fibrosis[1].

• Smiles:

  Cn1cc (CC (N) C (O) =O) c2ccccc12

• Molecular Formula:

  C12H14N2O2

• Molecular Weight:

  218.25

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  26988-72-7