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(Rac) -Indoximod

CAT: 0931-T60266Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0931-T60266Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
26988-72-7
Target
Others, Apoptosis, Indoleamine 2,3-Dioxygenase (IDO), IDO
Related Pathways
Apoptosis, Others, Metabolism
Bioactivity
(Rac) -Indoximod (1-Methyl-DL-tryptophan) is a potent inhibitor of indoleamine 2,3-dioxygenase (IDO) . Combined treatment with IFN-γ and (Rac) -Indoximod significantly suppresses the activity of α-SMA-expressing human cardiac myofibroblasts (hCMs) and promotes apoptosis by up-regulating the genes IRF-1, Fas, and FasL, effectively improving cardiac fibrosis[1].
Smiles
Cn1cc(CC(N)C(O)=O)c2ccccc12
Molecular Formula
C12H14N2O2
Molecular Weight
218.25
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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