Indoximod

• Target :

  Indoleamine 2,3-Dioxygenase (IDO) |||IDO

• Related Pathways :

  Metabolism

• Purity :

  0.9955

• Bioactivity :

  Indoximod (NLG-8189) is a methylated tryptophan with immune checkpoint inhibitory activity. Indoximod inhibits the enzyme indoleamine 2, 3-dioxygenase (IDO), which degrades the essential amino acid tryptophan, and may increase or maintain tryptophan levels important to T cell function. Tryptophan depletion is associated with immunosuppression involving T cell arrest and anergy.

• Smiles :

  Cn1cc(C[C@@H](N)C(O)=O)c2ccccc12

• Molecular Formula :

  C12H14N2O2

• Molecular Weight :

  218.25

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  110117-83-4