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H-151

CAT: 0931-T5674-06Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T5674-06Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
941987-60-6
Target
STING
Related Pathways
Immunology/Inflammation
Purity
0.9997
Bioactivity
H-151 is a highly potent and selective STING antagonist. H-151 covalently binds to Cys91 of STING and inhibits palmitoylation of Cys91, thereby inhibiting STING activity. H-151 can be used in the study of autoinflammatory diseases in vivo and ex vivo.
Smiles
CCc1ccc(NC(=O)Nc2c[nH]c3ccccc23)cc1
Molecular Formula
C17H17N3O
Molecular Weight
279.34
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea

H-151 is an inhibitor of the stimulator of interferon genes (STING) protein.

CAS Number941987-60-6
PubChem CID7616033
IUPAC Name1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea
Molecular FormulaC17H17N3O
Molecular Weight279.34
XLogP3.4
Topological Polar Surface Area56.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count1
Rotatable Bond Count3
Heavy Atom Count21
Formal Charge0
Complexity352
SMILES
CCC1=CC=C(C=C1)NC(=O)NC2=CNC3=CC=CC=C32
InChI
InChI=1S/C17H17N3O/c1-2-12-7-9-13(10-8-12)19-17(21)20-16-11-18-15-6-4-3-5-14(15)16/h3-11,18H,2H2,1H3,(H2,19,20,21)
InChIKey
UJZDIKVQFMCLBE-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 1-(4-ethylphenyl)-3-(1H-indol-3-yl)urea
CAS: 941987-60-6
CID: 7616033
Formula: C17H17N3O
MW: 279.34
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight279.34
XLogP33.4
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count1
Rotatable Bond Count3
Exact Mass279.137162174
Monoisotopic Mass279.137162174
Topological Polar Surface Area56.9 Ų
Heavy Atom Count21
Formal Charge0
Complexity352
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

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Alternative Products

CatalogName
584647H 151
inh-h151-5H-151

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