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Dbet57

CAT: 0931-T5440-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T5440-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1883863-52-2
Target
Apoptosis, Epigenetic Reader Domain, PROTACs
Related Pathways
PROTAC, Chromatin/Epigenetic, Apoptosis
Purity
0.9952
Bioactivity
DBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM , and inactive on BRD4BD2
Smiles
CC=1C2=C(N3C([C@H](CC(NCCNC4=C5C(C(=O)N(C5=O)C6C(=O)NC(=O)CC6)=CC=C4)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C
Molecular Formula
C34H31ClN8O5S
Molecular Weight
699.18
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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C07020-25mgDBET57
A19133-100DBET57 100mg
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A19133-500DBET57 500mg
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A19133-25DBET57 25mg
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