Linrodostat mesylate

• Target :

  Others|||IDO|||Indoleamine 2,3-Dioxygenase (IDO)

• Related Pathways :

  Others|||Metabolism

• Bioactivity :

  Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs) .

• Smiles :

  S(C)(=O)(=O)O.FC1=CC=2C(=CC=NC2C=C1)[C@@H]3CC[C@]([C@H](C(NC4=CC=C(Cl)C=C4)=O)C)(CC3)[H]

• Molecular Formula :

  C25H28ClFN2O4S

• Molecular Weight :

  507.02

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2221034-29-1