Linrodostat mesylate

CAT: 0931-MF-0040540-01Size: 25 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0040540-01Size:25 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
2221034-29-1
Target
Others|||IDO|||Indoleamine 2,3-Dioxygenase (IDO)
Related Pathways
Others|||Metabolism
Bioactivity
Linrodostat (BMS-986205, ONO-7701, and F001287) is a selective and orally active IDO1 inhibitor with potential immunomodulating and antineoplastic activities. By inhibiting IDO1 and reducing kynurenine in tumor cells, BMS-986205 restores and promotes the proliferation and activation of various immune cells and causes a reduction in tumor-associated regulatory T cells (Tregs) .
Smiles
S(C)(=O)(=O)O.FC1=CC=2C(=CC=NC2C=C1)[C@@H]3CC[C@]([C@H](C(NC4=CC=C(Cl)C=C4)=O)C)(CC3)[H]
Molecular Formula
C25H28ClFN2O4S
Molecular Weight
507.02
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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