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TM5441

CAT: 0931-T4254-06Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0931-T4254-06Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1190221-43-2
Target
PAI-1, Apoptosis
Related Pathways
Metabolism, Apoptosis
Purity
0.9909
Bioactivity
TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.It induces intrinsic cell death in several human cancer cells and attenuates Nω-nitro-1-arginine methyl ester-induced cardiac hypertension and vascular senescence.
Smiles
OC(=O)c1cc(Cl)ccc1NC(=O)COCC(=O)Nc1cccc(c1)-c1ccoc1
Molecular Formula
C21H17ClN2O6
Molecular Weight
428.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Chemical Information

TM-5441
CAS Number1190221-43-2
PubChem CID44250349
IUPAC Name5-chloro-2-[[2-[2-[3-(furan-3-yl)anilino]-2-oxoethoxy]acetyl]amino]benzoic acid
Molecular FormulaC21H17ClN2O6
Molecular Weight428.8
XLogP3.3
Topological Polar Surface Area118
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count6
Rotatable Bond Count8
Heavy Atom Count30
Formal Charge0
Complexity618
SMILES
C1=CC(=CC(=C1)NC(=O)COCC(=O)NC2=C(C=C(C=C2)Cl)C(=O)O)C3=COC=C3
InChI
InChI=1S/C21H17ClN2O6/c22-15-4-5-18(17(9-15)21(27)28)24-20(26)12-30-11-19(25)23-16-3-1-2-13(8-16)14-6-7-29-10-14/h1-10H,11-12H2,(H,23,25)(H,24,26)(H,27,28)
InChIKey
BGGMLMAPVODXAU-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of TM-5441
CAS: 1190221-43-2
CID: 44250349
Formula: C21H17ClN2O6
MW: 428.8
Interactive 3D Structure
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View on PubChemRaw 3D data

Alternative Products

CatalogName
QXB22143-01TM5441
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A19369-500TM5441 500mg
A19369-5TM5441 5mg
A19369-50TM5441 50mg
A19369-25TM5441 25mg
GTR19232990-01TM5441 sodium
A19369-100TM5441 100mg

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