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TM5441

CAT: 0931-T4254-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0931-T4254-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1190221-43-2
Target
PAI-1, Apoptosis
Related Pathways
Metabolism, Apoptosis
Purity
0.9909
Bioactivity
TM5441 is an orally bioavailable fibrinogen activator inhibitor-1 inhibitor that inhibits several cancer cell lines with IC50 values ranging from 13.9 to 51.1 μM.It induces intrinsic cell death in several human cancer cells and attenuates Nω-nitro-1-arginine methyl ester-induced cardiac hypertension and vascular senescence.
Smiles
OC(=O)c1cc(Cl)ccc1NC(=O)COCC(=O)Nc1cccc(c1)-c1ccoc1
Molecular Formula
C21H17ClN2O6
Molecular Weight
428.82
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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