NCT-503

• Target:

  TAM Receptor|||FLT|||Dehydrogenase

• Related Pathways:

  Metabolism|||Tyrosine Kinase/Adaptors|||Angiogenesis

• Purity:

  0.9984

• Bioactivity:

  NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=2.5 µM) with no activity against other dehydrogenases. NCT-503 has antitumor activity and inhibits the growth of PHGDH-dependent tumors.

• Smiles:

  Cc1cc(C)nc(NC(=S)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)c1

• Molecular Formula:

  C20H23F3N4S

• Molecular Weight:

  408.48

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1916571-90-8