NCT-503

CAT: 0931-T4213-01Size: 2 mgDry Ice: NoHazardous: No
CAT#:0931-T4213-01Size:2 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1916571-90-8
Target
TAM Receptor|||FLT|||Dehydrogenase
Related Pathways
Metabolism|||Tyrosine Kinase/Adaptors|||Angiogenesis
Purity
0.9984
Bioactivity
NCT-503 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor (IC50=2.5 µM) with no activity against other dehydrogenases. NCT-503 has antitumor activity and inhibits the growth of PHGDH-dependent tumors.
Smiles
Cc1cc(C)nc(NC(=S)N2CCN(Cc3ccc(cc3)C(F)(F)F)CC2)c1
Molecular Formula
C20H23F3N4S
Molecular Weight
408.48
Shipping Conditions
Cool pack
Storage Temperature
-20°C