NCT-502

• Target:

  Dehydrogenase

• Related Pathways:

  Metabolism

• Purity:

  0.996

• Bioactivity:

  NCT-502 (N- (4,6-dimethylpyridin-2-yl) -4-[5- (trifluoromethyl) pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 ?M against PHGDH.

• Smiles:

  Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1

• Molecular Formula:

  C18H20F3N5S

• Molecular Weight:

  395.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1542213-00-2