NCT-502

• Target :

  Dehydrogenase

• Related Pathways :

  Metabolism

• Purity :

  0.996

• Bioactivity :

  NCT-502 (N- (4,6-dimethylpyridin-2-yl) -4-[5- (trifluoromethyl) pyridin-2-yl]piperazine-1-carbothioamide) is a human phosphoglycerate dehydrogenase inhibitor, cytotoxic to PHGDH-dependent cancer cells. It decreases glucose-derived serine production and it has an IC50 of 3.7 ?M against PHGDH.

• Smiles :

  Cc1cc(C)nc(NC(=S)N2CCN(CC2)c2ccc(cn2)C(F)(F)F)c1

• Molecular Formula :

  C18H20F3N5S

• Molecular Weight :

  395.45

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1542213-00-2