Products for Research Use Only
RegisterLogin

NCT-58

CAT: 0931-T9996-01Size: 2 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0931-T9996-01Size:2 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
CAS Number
2411429-33-7
Target
Apoptosis, HSP
Related Pathways
Apoptosis, Cytoskeletal Signaling, Metabolism
Purity
0.996
Bioactivity
NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR) . NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of Akt phosphorylation. NCT-58 kills Trastuzumab-resistant breast cancer stem-like cells. NCT-58 induces apoptosis in HER2-positive breast cancer cells.
Smiles
COc1cc(NC(=O)c2ccc3OC(C)(C)C=Cc3c2OC)ccc1OCCC1CCCCN1
Molecular Formula
C27H34N2O5
Molecular Weight
466.57
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

Related Products

CatalogName
T38605-01NCT-504
T12196-01NCT-505
T25858-01NCT-10b
T4213-01NCT-503
T75344-01NCT-TFP
T16277-01NCT-502
T6903-01NCT-501
T12197-01NCT-506
T39485-01NCT-501 hydrochloride
T41159NCT 501 hydrochloride

Alternative Products

CatalogName
MBS3617508-01NCT-58
BA7138-5NCT-506
BA7139-10NCT-505
C3853-5NCT-503
XYB76597-01NCT-504
CXC08850-01NCT-501
MBS3607013NCT-507
GTR19175168-01NCT-502

Popular Products