EFdA-TP

• Target :

  Reverse Transcriptase|||HIV Protease|||Others|||DNA/RNA Synthesis

• Related Pathways :

  Proteases/Proteasome|||Cell Cycle/Checkpoint|||Microbiology/Virology|||DNA Damage/DNA Repair|||Others

• Bioactivity :

  EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways.

• Smiles :

  Nc1nc(F)nc2n(cnc12)[C@H]1C[C@H](O)[C@@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O1)C#C

• Molecular Formula :

  C12H15FN5O12P3

• Molecular Weight :

  533.195

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  950913-56-1