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EFdA-TP

CAT: 0931-T41110Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T41110Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
950913-56-1
Target
Reverse Transcriptase, HIV Protease, Others, DNA/RNA Synthesis
Related Pathways
Proteases/Proteasome, Cell Cycle/Checkpoint, Microbiology/Virology, DNA Damage/DNA Repair, Others
Bioactivity
EFdA-TP, a highly potent nucleoside reverse transcriptase (RT) inhibitor, exerts its inhibitory effect on RT-catalyzed DNA synthesis through both immediate and delayed chain termination mechanisms, commonly referred to as ICT and DCT, respectively. Additionally, EFdA-TP demonstrates its efficacy in inhibiting HIV-1 RT through multiple pathways.
Smiles
Nc1nc(F)nc2n(cnc12)[C@H]1C[C@H](O)[C@@](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)(O1)C#C
Molecular Formula
C12H15FN5O12P3
Molecular Weight
533.195
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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