SPDB-DM4

CAT: 0931-MF-0138313-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0138313-01Size:100 mg
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CAS Number
1626359-62-3
Target
Drug-Linker Conjugates for ADC
Related Pathways
Antibody-drug Conjugate/ADC Related
Bioactivity
SPDB-DM4 is a drug-linker conjugate designed for antibody-drug conjugate (ADC) applications, employing the maytansine-based payload DM4 (a tubulin inhibitor) connected through a SPDB linker. This compound demonstrates significant anti-tumor efficacy.
Smiles
[H][C@@]12C[C@@](O)(NC(=O)O1)[C@]([H])(OC)\C=C/C=C(C)\Cc1cc(OC)c(Cl)c(c1)N(C)C(=O)C[C@H](OC(=O)[C@H](C)N(C)C(=O)CCC(C)(C)SSCCCC(=O)ON1C(=O)CCC1=O)[C@]1(C)O[C@H]1[C@@H]2C
Molecular Formula
C46H63ClN4O14S2
Molecular Weight
995.59
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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