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AZD-4877

CAT: 931-T9682-01Size: 1 mgDry Ice: NoHazardous: No
1 mgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
758722-49-5
Target
Apoptosis|||Kinesin
Related Pathways
Apoptosis|||Cytoskeletal Signaling
Purity
0.9987
Bioactivity
AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC) .
Smiles
C(N(C(=O)C1=CC=C(C)C=C1)CCCN)(C(C)C)C=2N(CC3=CC=CC=C3)C(=O)C4=C(N2)SN=C4C
Molecular Formula
C28H33N5O2S
Molecular Weight
503.66
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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