AZD-4877

• Target :

  Apoptosis|||Kinesin

• Related Pathways :

  Apoptosis|||Cytoskeletal Signaling

• Purity :

  0.9987

• Bioactivity :

  AZD-4877 is a potent spindle kinesin (Eg5) inhibitor with an IC50 value of 2 nM. AZD-4877 is an alternative configuration of Ispinesib that inhibits mitosis, induces the formation of a unipolar spindle phenotype, and mediates apoptosis. AZD-4877 has antitumor activity and inhibits circulating peripheral blood mononuclear cells (PBMC) .

• Smiles :

  C(N(C(=O)C1=CC=C(C)C=C1)CCCN)(C(C)C)C=2N(CC3=CC=CC=C3)C(=O)C4=C(N2)SN=C4C

• Molecular Formula :

  C28H33N5O2S

• Molecular Weight :

  503.66

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  758722-49-5