RM-018

• Target:

  Others|||Kras|||Ras

• Related Pathways:

  Others|||GPCR/G Protein|||MAPK

• Bioactivity:

  RM-018 is a powerful tricomplex inhibitor that specifically targets the active state of KRAS G12C. It exhibits unique functional characteristics and possesses the ability to bind and inhibit both KRAS G12C and KRAS G12C/Y96D, potentially overcoming resistance.

• Smiles:

  CCn1c(c2CC(C)(C)COC(=O)[C@@H]3CCCN(N3)C(=O)[C@H](Cc3cccc(c3)-c3ccc1c2c3)NC(=O)[C@H](C(C)C)N(C)C(=O)[C@H]1CCN(C1)C(=O)C#CCN1CCOCC1)-c1cccnc1[C@H](C)OC

• Molecular Formula:

  C56H72N8O8

• Molecular Weight:

  985.24

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  2641993-55-5