LLW-018

• Target :

  PD-1/PD-L1

• Related Pathways :

  Apoptosis|||Cell Cycle/Checkpoint|||Immunology/Inflammation

• Bioactivity :

  LLW-018 is a potent PD-1/PD-L1 inhibitor with an IC50 value of 2.61 nM. It can disrupt the PD-1/PD-L1 interaction, with a cell-based PD-1/PD-L1 blocking bioassay IC50 value of 0.88 ?M. LLW-018 holds potential for research in immune-related diseases.

• Smiles :

  ClC1=CC(=CC=C1OCC=2C=CC=C(C=3C=CC=C4C(=NSC43)NC5=CC=C(C=C5Cl)CNC(CO)CO)C2C)CNC(CO)CO

• Molecular Formula :

  C35H38Cl2N4O5S

• Molecular Weight :

  697.67

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  3049369-11-8