MK-4688

• Target:

  MDM-2/p53|||Others

• Related Pathways:

  Apoptosis|||Others

• Bioactivity:

  MK-4688 is a potent inhibitor of the HDM2-p53 protein-protein interaction.

• Smiles:

  [H][C@@]12CCC[C@@]1([H])N(CCO2)c1nc2cc(nc(-c3cncc(Cl)c3)c2n1C[C@H]1CC[C@H](C)CC1)-c1noc(=O)[nH]1|wU:5.6,28.32,wD:1.0,31.36,(-.16,3.07,;,1.54,;-1.46,2.02,;-2.37,.77,;-1.46,-.48,;;-.16,-1.53,;1.33,-.77,;2.67,,;2.67,1.54,;1.33,2.31,;1.33,-2.31,;.09,-3.22,;.56,-4.68,;-.21,-6.01,;.56,-7.35,;2.1,-7.35,;2.87,-6.01,;4.41,-6.01,;5.18,-4.68,;6.72,-4.68,;7.49,-6.01,;6.72,-7.35,;7.49,-8.68,;5.18,-7.35,;2.1,-4.68,;2.58,-3.22,;4.04,-2.74,;4.36,-1.23,;3.22,-.2,;3.54,1.3,;5,1.78,;5.32,3.29,;6.15,.75,;5.83,-.76,;-.21,-8.68,;-1.74,-8.84,;-2.06,-10.35,;-.72,-11.12,;-.56,-12.65,;.42,-10.09,)|

• Molecular Formula:

  C28H32ClN7O3

• Molecular Weight:

  550.06

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1616428-79-5