QL-X-138

• Target:

  Anti-infection|||MNK|||BTK|||Virus Protease

• Related Pathways:

  MAPK|||Microbiology/Virology|||Angiogenesis|||Tyrosine Kinase/Adaptors

• Purity:

  0.995

• Bioactivity:

  QL-X-138 is a potent and selective BTK and MNK dual kinase inhibitor that binds covalently to BTK and non-covalently to MNK. The IC50 values of QL-X-138 are 9.4 nM for BTK, 107.4 nM for MNK1, 26 nM for MNK2, and 3.5 ?M against Dengue 2. QL-X-138 is used in the study of B-cell malignancies and B-cell malignant tumors.

• Smiles:

  O=C1N(C2=C3C(=NC=C2C=C1)C=CC(=C3)C=4C=NNC4)C5=CC(NC(C=C)=O)=C(C)C=C5

• Molecular Formula:

  C25H19N5O2

• Molecular Weight:

  421.45

• Shipping Conditions:

  Cool pack

• Storage Temperature:

  -20°C

• CAS Number:

  1469988-63-3