QL-1200186

• Target :

  JAK

• Related Pathways :

  JAK/STAT signaling|||Stem Cells|||Angiogenesis|||Chromatin/Epigenetic|||Tyrosine Kinase/Adaptors

• Bioactivity :

  QL-1200186 is an orally active, selective TYK2 inhibitor that, upon dose-dependent oral administration, suppresses interferon-? (IFN?) production following interleukin-12 (IL-12) stimulation and markedly improves skin lesions in a psoriatic mouse model [1].

• Smiles :

  O=C(NC)C1=CN=C2C=C1NC3=CC(=CC(C4=NN(C=C4)C)=C3OC)CCOCC5=NC(=CC=C5)N2

• Molecular Formula :

  C26H27N7O3

• Molecular Weight :

  485.54

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  2848664-42-4