Factor D inhibitor 6

CAT: 0931-MF-0096455-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0931-MF-0096455-01Size:1 mg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
1386455-51-1
Target
Complement System|||Others
Related Pathways
Immunology/Inflammation|||Others
Bioactivity
Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.
Smiles
[H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)N[C@H](C)c1cccc(Cl)c1F)C(=O)Cn1nc(C(N)=O)c2ccncc12
Molecular Formula
C23H22ClFN6O3
Molecular Weight
484.92
Shipping Conditions
Cool pack
Storage Temperature
-20°C

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