Factor D inhibitor 6

CAT: 0931-T38803-01Size: 1 mgDry Ice: NoHazardous: No

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CAT#:0931-T38803-01Size:1 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

1386455-51-1

Target

Complement System, Others

Related Pathways

Immunology/Inflammation, Others

Bioactivity

Factor D inhibitor 6 is a potent, highly selective, and orally active compound that specifically inhibits the activity of factor D (FD) with an IC50 of 30 nM and a Kd of 6 nM. It does not exhibit inhibitory effects against factor B, classical and lectin complement-pathway activation, or a broad array of receptors, ion channels, kinases, and proteases.

Smiles

[H][C@]12C[C@@]1([H])N([C@@H](C2)C(=O)N[C@H](C)c1cccc(Cl)c1F)C(=O)Cn1nc(C(N)=O)c2ccncc12

Molecular Formula

C23H22ClFN6O3

Molecular Weight

484.92

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Factor D inhibitor 6

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