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P38α inhibitor 6

CAT: 0931-T206938-01Size: 10 mgDry Ice: NoHazardous: No
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CAT#:0931-T206938-01Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Target
MDM-2/p53, Apoptosis, Caspase, Bcl-2 Family, p38 MAPK
Related Pathways
MAPK, Apoptosis, Proteases/Proteasome
Bioactivity
P38α inhibitor6 (compound 19) is a p38α inhibitor with an IC50 value of 0.68 μM. It induces apoptosis, arrests the cell cycle in the G0 and G2/M phases, reduces TNF-α concentration, upregulates the expression of the tumor suppressor gene p53, increases the Bax/BCL-2 ratio, and activates caspase3/7.
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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